Hospital Emergency Vantilators

ventilator is a machine that provides mechanical ventilation by moving breathable air into and out of the lungs, to deliver breaths to a patient who is physically unable to breathe, or breathing insufficiently. Modern ventilators are computerized microprocessor controlled machines, but patients can also be ventilated with a simple, hand-operated bag valve mask. Ventilators are chiefly used in intensive care medicinehome care, and emergency medicine (as standalone units) and in anesthesiology (as a component of an anesthesia machine).

Examples of commonly used intensive care ventilators: A. Dräger Infinity V500, B. Hamilton G5, C. Maquet Servo i, D. Covidien PB840. Source: Tobin MJ: Principles and Practice of Mechanical Ventilation, 3rd Edition: Copyright © The McGraw-Hill Companies, Inc. All rights reserved.

Ventilators are sometimes called respirators, a term commonly used for them in the 1950s (particularly the “Bird respirator“). However, in contemporary hospital and medical terminology, a respirator is a protective face mask.[1]


In its simplest form, a modern positive pressure ventilator consists of a compressible air reservoir or turbine, air and oxygen supplies, a set of valves and tubes, and a disposable or reusable “patient circuit”. The air reservoir is pneumatically compressed several times a minute to deliver room-air, or in most cases, an air/oxygen mixture to the patient. If a turbine is used, the turbine pushes air through the ventilator, with a flow valve adjusting pressure to meet patient-specific parameters. When over pressure is released, the patient will exhale passively due to the lungs‘ elasticity, the exhaled air being released usually through a one-way valve within the patient circuit called the patient manifold.

Ventilators may also be equipped with monitoring and alarm systems for patient-related parameters (e.g. pressure, volume, and flow) and ventilator function (e.g. air leakage, power failure, mechanical failure), backup batteries, oxygen tanks, and remote control. The pneumatic system is nowadays often replaced by a computer-controlled turbopump.

Modern ventilators are electronically controlled by a small embedded system to allow exact adaptation of pressure and flow characteristics to an individual patient’s needs. Fine-tuned ventilator settings also serve to make ventilation more tolerable and comfortable for the patient. In Canada and the United States, respiratory therapists are responsible for tuning these settings, while biomedical technologists are responsible for the maintenance. In the United Kingdom and Europe the management of the patient’s interaction with the ventilator is done by critical care nurses.

The patient circuit usually consists of a set of three durable, yet lightweight plastic tubes, separated by function (e.g. inhaled air, patient pressure, exhaled air). Determined by the type of ventilation needed, the patient-end of the circuit may be either noninvasive or invasive.

Noninvasive methods, such as continuous positive airway pressure (CPAP) and non-invasive ventilation, which are adequate for patients who require a ventilator only while sleeping and resting, mainly employ a nasal mask. Invasive methods require intubation, which for long-term ventilator dependence will normally be a tracheotomy cannula, as this is much more comfortable and practical for long-term care than is larynx or nasal intubation.

Life-critical system

Because failure may result in death, mechanical ventilation systems are classified as life-critical systems, and precautions must be taken to ensure that they are highly reliable, including their power-supply.

Mechanical ventilators are therefore carefully designed so that no single point of failure can endanger the patient. They may have manual backup mechanisms to enable hand-driven respiration in the absence of power (such as the mechanical ventilator integrated into an anaesthetic machine). They may also have safety valves, which open to atmosphere in the absence of power to act as an anti-suffocation valve for spontaneous breathing of the patient. Some systems are also equipped with compressed-gas tanks, air compressors or backup batteries to provide ventilation in case of power failure or defective gas supplies, and methods to operate or call for help if their mechanisms or software fail.


The history of mechanical ventilation begins with various versions of what was eventually called the iron lung, a form of noninvasive negative pressure ventilator widely used during the polio epidemics of the twentieth century after the introduction of the “Drinker respirator” in 1928, improvements introduced by John Haven Emerson in 1931,[2] and the Both respirator in 1937. Other forms of noninvasive ventilators, also used widely for polio patients, include Biphasic Cuirass Ventilation, the rocking bed, and rather primitive positive pressure machines.[2]

In 1949, John Haven Emerson developed a mechanical assister for anaesthesia with the cooperation of the anaesthesia department at Harvard University. Mechanical ventilators began to be used increasingly in anaesthesia and intensive care during the 1950s. Their development was stimulated both by the need to treat polio patients and the increasing use of muscle relaxants during anaesthesia. Relaxant drugs paralyse the patient and improve operating conditions for the surgeon but also paralyse the respiratory muscles.

A machine with hoses and gauges on a wheeled cart

An East-Radcliffe respirator model from the mid-twentieth century

In the United Kingdom, the East Radcliffe and Beaver models were early examples. The former used a Sturmey-Archer bicycle hub gear to provide a range of speeds, and the latter an automotive windscreen wiper motor to drive the bellows used to inflate the lungs.[3] Electric motors were, however, a problem in the operating theatres of that time, as their use caused an explosion hazard in the presence of flammable anaesthetics such as ether and cyclopropane. In 1952, Roger Manley of the Westminster Hospital, London, developed a ventilator which was entirely gas-driven and became the most popular model used in Europe. It was an elegant design, and became a great favourite with European anaesthetists for four decades, prior to the introduction of models controlled by electronics. It was independent of electrical power and caused no explosion hazard. The original Mark I unit was developed to become the Manley Mark II in collaboration with the Blease company, which manufactured many thousands of these units. Its principle of operation was very simple, an incoming gas flow was used to lift a weighted bellows unit, which fell intermittently under gravity, forcing breathing gases into the patient’s lungs. The inflation pressure could be varied by sliding the movable weight on top of the bellows. The volume of gas delivered was adjustable using a curved slider, which restricted bellows excursion. Residual pressure after the completion of expiration was also configurable, using a small weighted arm visible to the lower right of the front panel. This was a robust unit and its availability encouraged the introduction of positive pressure ventilation techniques into mainstream European anesthetic practice.

The 1955 release of Forrest Bird‘s “Bird Universal Medical Respirator” in the United States changed the way mechanical ventilation was performed, with the small green box becoming a familiar piece of medical equipment.[4] The unit was sold as the Bird Mark 7 Respirator and informally called the “Bird”. It was a pneumatic device and therefore required no electrical power source to operate.

In 1965, the Army Emergency Respirator was developed in collaboration with the Harry Diamond Laboratories (now part of the U.S. Army Research Laboratory) and Walter Reed Army Institute of Research. Its design incorporated the principle of fluid amplification in order to govern pneumatic functions. Fluid amplification allowed the respirator to be manufactured entirely without moving parts, yet capable of complex resuscitative functions.[5] Elimination of moving parts increased performance reliability and minimized maintenance.[6] The mask is composed of a poly(methyl methacrylate) (commercially known as Lucite) block, about the size of a pack of cards, with machined channels and a cemented or screwed-in cover plate.[7] The reduction of moving parts cut manufacturing costs and increased durability.[6]

The bistable fluid amplifier design allowed the respirator to function as both a respiratory assistor and controller. It could functionally transition between assistor and controller automatically, based on the patient’s needs.[7][6] The dynamic pressure and turbulent jet flow of gas from inhalation to exhalation allowed the respirator to synchronize with the breathing of the patient.[8]

Intensive care environments around the world revolutionized in 1971 by the introduction of the first SERVO 900 ventilator (Elema-Schönander). It was a small, silent and effective electronic ventilator, with the famous SERVO feedback system controlling what had been set and regulating delivery. For the first time, the machine could deliver the set volume in volume control ventilation.

Ventilators used under increased pressure (hyperbaric) require special precautions and few ventilators can operate under these conditions.[9] In 1979, Sechrist Industries introduced their Model 500A ventilator which was specifically designed for use with hyperbaric chambers.[10]

Microprocessor ventilators

Microprocessor control led to the third generation of intensive care unit (ICU) ventilators, starting with the Dräger EV-A[11] in 1982 in Germany which allowed monitoring the patients breathing curve on an LCD monitor. One year later followed Puritan Bennett 7200 and Bear 1000, SERVO 300 and Hamilton Veolar over the next decade. Microprocessors enable customized gas delivery and monitoring, and mechanisms for gas delivery that are much more responsive to patient needs than previous generations of mechanical ventilators.[12]

In 1991, the SERVO 300 ventilator series was introduced, enabling treatment of all patient categories from adult to neonate with one ventilator. The SERVO 300 series had a unique gas delivery system with rapid flow-triggering response.

In 1999, the new LTV (Laptop Ventilator) Series was significantly smaller than other ventilators of the time, weighing approximately 6.4 kg (14 lb) and about the size of a laptop computer. This design kept the same functionality of the in-hospital ventilators while allowing patient mobility.

A modular concept was introduced with SERVO-i in 2001, with one ventilator model throughout the ICU department, instead of a fleet of various models and brands for different user needs. With the modular ventilator, ICU departments could choose the modes and options, software and hardware needed for a particular patient category.

In the twenty-first century small portable ventilators like the SAVe II have been manufactured for forward combat use.[13]

Open-source ventilator

An open-source ventilator is a disaster-situation ventilator made using a freely-licensed design, and ideally, freely-available components and parts. Designs, components, and parts may be anywhere from completely reverse-engineered to completely new creations, components may be adaptations of various inexpensive existing products, and special hard-to-find and/or expensive parts may be 3D printed instead of sourced.[14][15]

One small, early prototype effort was the Pandemic Ventilator created sometime in 2008 (per oldest comments) during the resurgence of H5N1 avian influenza that began in 2003, and so named “because it is meant to be used as a ventilator of last resort during a possible avian (bird) flu pandemic.”

A major worldwide design effort began during the 2019-2020 coronavirus pandemic after a Hackaday project was started,[16][non-primary source needed] in order to respond to expected ventilator shortages causing higher mortality rate among severe patients.

On March 20, 2020, the Irish Health Service[17] began reviewing designs.[18] A prototype is being designed and tested in Colombia.[19].

The Polish company Urbicum reports successful testing[20] of a 3D-printed open-source prototype device called VentilAid. The makers describe it as a last resort device when professional equipment is missing. The design is publicly available.[21] The first Ventilaid prototype requires compressed air to run.

On March 21, 2020 the New England Complex Systems Institute (NECSI) began maintaining a strategic list of open source designs being worked on.[22][23] The NECSI project considers manufacturing capability, medical safety and need for treating patients in various conditions, speed dealing with legal and political issues, logistics and supply.[24] NECSI is staffed with scientists from Harvard and MIT and others who have an understanding of pandemics, medicine, systems, risk, and data collection.[24]

2020 coronavirus pandemi

The pandemic has led to shortages of essential goods and services – from hand sanitizers to masks to beds to ventilators. Several countries have already experienced a shortage of ventilators.[25]

In 2006 (under President George W. Bush), a federal agency, the Biomedical Advanced Research and Development Authority (BARDA), realized that the U.S. was likely to have an epidemic of respiratory disease and would need more ventilators, so they awarded a $6 million contract to Newport Medical Instruments, a small company in California, to make 40,000 ventilators for under $3,000 apiece. In 2011, Newport sent 3 prototypes to the Centers for Disease Control. In 2012, Covidien, a $12 billion/year medical device manufacturer, which manufactured more expensive competing ventilators, bought Newport for $100 million. Covidien delayed and in 2014 cancelled the contract. BARDA started over again with a new company, Philips, and in July 2019, the FDA approved the Philips ventilator, and the government ordered 10,000 ventilators for delivery in mid-2020.[26]

Export restraints on medical supplies during a pandemic

Fifty-four governments, including many in Europe and Asia, imposed restrictions on medical supply exports in response to the coronavirus pandemic.[27]

Major manufacturers

ICU ventilators
Manufacturer Country Market share (2019)
Getinge Sweden 22%
Hamilton Medical USA, Switzerland 22%
Dräger Germany 16%
Mindray China 10%
Medtronic Ireland, USA 5%
Löwenstein Medical Germany 3%
Vyaire Medical USA 3%
GE Healthcare USA 3%
Philips Respironics Netherlands 3%
Others 15%
Categories Category #1/Category #2

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